Paul L. Edmiston

Paul L. Edmiston, Associate Professor of Chemistry, is a native of Tucson, Arizona. He received his B.S. degree in Chemistry at Pepperdine University in 1993 and his Ph.D. from the University of Arizona in 1997. His Ph.D. work involved measuring orientation distributions of hydrated protein films immobilized at solid liquid interfaces using the combination of absorbance linear dichroism performed in an integrated optical waveguide total internal reflectance geometry and total internal reflectance fluorescence anistropy. Paul was a Camille and Henry Dreyfus Fellow at The College of Wooster under the direction of Charles L. Borders, Jr. from 1997-99. In the Fall of 1999 he joined the department as Assistant Professor. His research interests include the development of chemical sensors using molecular imprinting techniques. He currently teaches analytical chemistry, instrumental analysis, general chemistry, forensic science, Techniques in Biochemistry and Molecular Biology, and First-Year Seminar at Wooster. In his free time Paul enjoys bicycling, mountain bike riding, and backpacking.

Recent Publications:

Paul L. Edmiston, Laura A. Underwood. Absorption of Dissolved Organic Species from Water Using Organically Modified Ailica that Swells. Separation and Purification Technology, 2009, 66, 532-540.

Colleen M. Burkett, Laura A. Underwood, Rebecca S. Volzer, Jessi A. Baughman, Paul L. Edmiston. Organic-Inorganic Hybrid Materials that Rapidly Swell in Non-Polar Liquids: Nanoscale Morphology and Swelling Mechanism. Chemistry of Materials, 2008, 20, 1312-1321.

Michael J. Jourden, Callisia N. Clarke, Allyson K. Palmer, Emily J. Barth, Rebecca C. Prada, Robyn N. Hale, Dean Fraga, Mark J. Snider, Paul L. Edmiston. Changing the Substrate Specificity of Creatine Kinase from Creatine to Glycocyamine: Evidence for a Highly Evolved Active Site. Biochim. Biophys. Acta 2007, 1774, 1519-1527.

Natalie R. Walker, Matthew J. Linman, Margaret M. Timmers, Stacey L. Dean, Colleen M. Burkett, Julie A. Lloyd, Joel D. Keelor, Brandi M. Baughman, Paul L. Edmiston. Selective Detection of Gas-Phase TNT by Integrated Optical Waveguide Spectrometry Using Molecularly Imprinted Sol-Gel Sensing Films. Analytica Chimica. Acta 2007, 593, 82-91.

Jeffrey F. Ohren, Melisa L. Kundracik, Charles L. Borders, Jr., Paul L. Edmiston, Ronald E. Viola. Structural asymmetry and intersubunit communication in muscle creatine kinase. Acta Crystallographica, Section D: Biological Crystallography 2007, D63, 381-389.

Catherine A. Carlson, Julie A. Lloyd, Stacey L. Dean, Natalie R. Walker, and Paul L. Edmiston; Sensor for Fluorene Based on the Incorporation of an Environmentally Sensitive Fluorophore Proximal to a Molecularly Imprinted Binding Site. Analytical Chemistry 2006, 78, 3537-3542.

Colleen M. Burkett, Paul L. Edmiston; Highly Swellable Sol-Gels Prepared by Chemical Modification of Silanol Groups Prior to Drying. Journal of Non-Crystalline Solids 2005, 351, 3174-3178.

Michael J. Jourden, Michael J. Thomenius, Lindsay A. Horst, Melissa M. Barty, Melissa J. Brym, Guy B. Mulligan, Ryan M. Almeida, Betsy A. Kersteen, Nichole R. Myers, Mark J. Snider, Charles L. Borders Jr., Paul L. Edmiston; Transition State Stabilization by Six Arginines Clustered in the Active Site of Creatine Kinase. Biochim. Biophys. Acta 2005, 1751, 178-183.

J. M. Cox, C. A. Davis, C. Chan, M. J. Jourden, A. M. Jorjorian, M. J. Brym, M. J. Snider, C. L. Borders, Jr., P. L. Edmiston; Generation of an active site monomer of rabbit muscle creatine kinase by site-directed mutangensis: The effect of quaternary structure on catalysis and stability. Biochemistry 2003, 42, 1863-1871.

J. A. Lloyd, P. L. Edmiston; Preferential extraction of hydorcarbons from fire debris samples by solid phase microextraction. J. Forensic Sciences 2003, 48, 130-134.

A. L. Graham, C. A. Carlson, P. L. Edmiston; Development and Characterization of Molecularly Imprinted Sol-Gel Materials for the Selected Detection of DDT. Analytical Chemistry, 2002, 74, 458-467.

P. L. Edmiston; A New Start to Advanced Analytical Laboratory: Comparison of the Performance Characteristics of Various Instruments. J. Chem. Ed., 2002, 79, 616-618.

P. L. Edmiston and R. Q. Thompson; Ohio's Crime Solvers: Analytical Chemistry Students Making the Case for Homicide. Analytical Chemistry, 2001, 73, 678A-684A.

P. L. Edmiston and T. R. Williams; An Analytical Experiment in Error Analysis; Repeated Determination of Glucose Using Commercail Glucometers; J. Chem. Educ. 77, 377-379 (2000).

P. L. Edmiston and S. S. Saavedra; Uranium Oxide Doped integrated Optical Waveguides Fabricated from a Sol-Gel Pocess; Chemistry of Materials, 1997, 9, 2599-2603.

P. L. Edmiston and S. S. Saavedra; Molecular Orientation Distriution in Protein Films III. Yeast Cytochrome c Films Immobilized on Pyridine Disulfide Capped Phospholipid Bilayers; Biophysical Journal, 1998, 74, 999-1006.

P. L. Edmiston and S. S. Saavedra; Molecular Orientation Distriution in Protein Films IV. A Multilayer Composed of Yeast Cytochrome c Bound to an Intermediate Streptavidin Layer to a Planar Supported Phospholipid Bilayer; Journal of the American Chemical Society, 1998, 120, 1665-1671.

Invited Lectures and Papers/Posters Presented at Professional Meetings:

P. L. Edmiston; Forensic Science as a Centerpiece for Analytical Chemistry Laboratory; PITTCON 2005. Orlando, FL, March 2005.

C. A. Carlson, S. L. Dean, P. L. Edmiston; Development of a Molecularly Imprinted Sol-Gel Sensor for Fluorene; ACS Fall Meeting, Boston, MA, August 2002.

P. L. Edmiston; Sol-Gel Molecular Imprinting for Sensor Development; University of Akron, 2002.

A. L. Graham, C. A. Carlson, P. L. Edmiston; Development and Characterization of Molecularly Imprinted Sol-Gel Materials for the Selected Detection of DDT; PITTCON, New Orleans, LA, March 5-9, 2001

C. Carlson*, P. L. Edmiston.; Fluorescence and Infrared Spectoscopic Analysis of the R134A Mutant of Rabbit Muscle Creatine Kinase; Central Regional ACS Meeting, Covington, KY, May 2000.

A. L. Graham* and P. L. Edmiston; Development and Characterization of Porous Sol-Gel Thin Films for the Selective Detection of DDT (1,1-Bis(4-Chlorophenyl)-2,2,2-Trichloroethane) via Molecular Imprinting Techniques; Central Regional ACS Meeting, Covington, KY, May 2000.

P. L. Edmiston, K. L. Schavolt*, E. R. K. Gbeddy*, M. J. Thomenius*, E. A. Kersteen*, N. R. Moore* and C. L. Borders, Jr.; Kinetic Analysis of Arginine-285 Mutants of Rabbit Muscle Creatine Kinase; 16th Annual Enzymes Mechanisms Conference, Napa, CA, January 1999.

P. L. Edmiston, J. E. Lee, and S. S. Saavedra; Dipole Orientation Distributions in Organic Monolayers by Planar Waveguide ATR and Fluorescence Anisotropy; 69th Colloid & Surface Science Symposium, Salt Lake City, UT, June 1995.

P. L. Edmiston, J. E. Lee, L. L. Wood, S. S. Cheng, and S. S. Saavedra; Orientation Distributions in Hydrated Protein Films; FACSS Conference, Kansas City, MO, October 1996.

P. L. Edmiston, J. E. Lee, L. L. Wood, S. S. Cheng, and S. S. Saavedra; Orientation Distributions in Hydrated Protein Films; ACS Conference, San Francisco, CA, April 1997.

Recent Grant Support

"Active Sampling and Reactive Chemistry for the Enhanced Detection of Explosives." NSF by David Gottfried, Daniel Campbell, Jayme Caspall and Paul Edmiston $800,000.

"Optical Sensors for the Detection of Vapor Phase Explosives Using Molecularly Imprinted Sol-Gel Materials: Integration of Research and Learning Using Forensic Science." NSF-CAREER, $400,000, by P. L. Edmiston.

Dreyfus Supplemental Award, $10,000, by P. L. Edmiston.

Dreyfus Faculty Start-Up Award, $20,000, by P. L. Edmiston.

"Universal Application of a GC-MS in Science Education: Integrating Courses and Programs for Pre-College, Non-Science, and Science Students Using Instrumental Teaching Assistants," NSF-CCLI, $48,989, by P. L. Edmiston, D. L. Powell, and T. R. Williams.

"Creatine Kinase: Structure/Function Relationships of Conserved Residues by Site-Directed Mutagenesis," NSF-RUI, $192,000, by C. L. Borders, Jr. and P. L. Edmiston.