Paul L. Edmiston

Department/Affiliation: Chemistry
Phone: 330-263-2113
Office Address: 213 Severance Hall
Email: pedmiston@wooster.edu
Web Site: ABS Materials, Inc.

Degrees

• B.S., Pepperdine University 1993
• Ph.D., University of Arizona 1997

Areas of Research

Advanced materials for water purification usign swellable glass; development of chemical sensors based on molecularly imprinted materials. (There is an article in the Wooster Magazine Summer 2009 about Paul's research.)

• U.S. Department of Energy
• U.S. EPA

Courses Taught

• CHEM 101:  Chemistry and the World in Which We Live
• CHEM 110:  Introductory Chemistry
• CHEM 120:  Principles of Chemistry
• CHEM 215:  Analytical Chemistry
• CHEM 316:  Instrumental Analysis
• BCMB 303:  Techniques
• BCMB 401:  Introduction to Independent Study
• First Year Seminar

Three Minutes with Paul Edmiston

I.S. Projects

• Rachel Bennett: Development of a Sensor for Gas-Phase Triacetone Triperoxide Using Waveguide Interferometry
• Deanna Pickett: In Situ Remediation of Groundwater Contaminants Trichloroethylene and Perchloroethylene by Swellable Organo Silica-Nano Zero Valent Iron Composite Materials
• Laura West: Diagnosis of Active Tuberculosis Infection Using Animated Hybrid Organic-Inorganic Materials

Awards and Professional Memberships

• National Science Foundation (2010-11), "Produced Water Treatment Using Animated Organosilicas that Rapidly and Reversible Swell
• Department of Energy, SBIR (2010-11), "Frac Fluid and Flow Back Water Treatment Using Animated Organosilicas that Rapidly and Reversible Swell
• National Science Foundation RUI (2009-11), "Engineering Organosilica Materials that Rapidly and Reversible Swell for Water Remediation"
• MIT Clean Energy Prize (2009), Finalist Team, Clean Hydrocarbons Category Winner
• National Science Foundation EXP (2007-10)
• National Science Foundation CAREER Award (2003-08)
• American Chemical Society (ACS)

Publications

• Edmiston, P. L.; Campbell, D. P.; Gottfried, D. S.; Baughman, J.; Timmers, M. M.; Detection of Trinitrotoluene in the Parts-per-Trillion Range Using Waveguide Interferometry. Sensor & Actuators B, 143, 574-582 (2010).
• Edmiston, P. L.; Underwood, L. A. Absorption of Dissolved Organic Species from Water Using Organically Modified Silica that Swells. Separation and Purification Technology, 66, 532-540 (2009).
• Burkett, C. M.*; Underwood, L. A.*, Volzer, R. S.*; Baughman, J. A.*; Edmiston, P. L. Organic-Inorganic Hybrid Materials that Rapidly Swell in Non-Polar Liquids: Nanoscale Morphology and Swelling Mechanism. Chemistry of Materials 20, 1312-1321 (2008).
• Jourden, M. J.*; Clarke, C. N.*; Palmer, A. K.*; Barth, E. J.*; Prada, R. C.*; Hale, R. N.*; Fraga, D. Snider, M. J.; Edmiston, P. L. Changing the Substrate Specificity of Creatine Kinase from Creatine to Glycocyamine: Evidence for a Highly Evolved Active Site”Biochim. Biophys. Acta, 1774, 1519-1527 (2007).
• Walker, N. R.*; Linman M. J.*; Timmers, M. M.*; Dean S. L.*; Burkett, C. M.*; Lloyd, J. A.*; Keelor, J. D.*; Baughman, B. M.*; Edmiston, P. L.. Selective Detection of Gas-Phase TNT by Integrated Optical Waveguide Spectrometry Using Molecularly Imprinted Sol-Gel Sensing Films. Analytica Chimica Acta, 593, 82-91 (2007).
• Ohren, J. F.; Kundracik, M. L.*; Borders, C. L.; Edmiston P. L.; and Viola R. E.  Structural Asymmetry and Intersubunit Communication in Muscle Creatine Kinase. Acta Cryst. D63, 381-389 (2007).
• Carlson, C. A.*; Lloyd, J. A.*; Dean, S. L.*; Walker, N. R.*, Edmiston, P. L. Sensor for Fluorene Based on the Incorporation of an Environmentally Sensitive Fluorophore Proximal to a Molecularly Imprinted Binding Site, Anal. Chem., 78 (11), 3537 -3542 (2006).
• Burkett, C. M.*; Edmiston P. L.; Highly Swellable Sol-Gels Prepared  by Chemical Modification of Silanol Groups Prior to Drying. J  Non-Crystalline Solids ,351 , 3174-3178 (2005).
• Jourden, M. J.*; Geiss, P.*; Thomenius, M. J.*; Horst, L. A.*; Barty, M. M.*; Brym, M. J.*; Mulligan, G.B.*; Almeida, R.M.*; Kersteen, E.A.*; Myers, N.R.*; Snider, M. J.; Borders Jr., C. L.; Edmiston, P.L.; Transition State  Stabilization by Six Arginines Clustered in the Active Site of Creatine Kinase. Biochim. Biophys. Acta  ,1751 , 178-183 (2005).
• Cox, J. M.*, Davis, C. A.*, Chan, C.*, Jourden, M. J.*, Jorjorian, A. D.*, Brym, M. J.*, Snider, M. J., Borders, Jr., C. L., Edmiston, P. L. Generation of an Active Monomer of Rabbit Muscle Creatine Kinase by Site-Directed Mutagenesis: The Effect of Quaternary Structure on Catalysis and Stability. Biochemistry 42, 1863-1871 (2003).
• Borders, C. L.; MacGregor, K. M.*; Edmiston, P. L.; Gbeddy, E. R. K.*; Thomenius, M. J.*; Mulligan, G. B.*; Snider, M. J. Creatine Kinase: Asparagine 285 Plays a Key Role in Transition State Stabilization and Determination of the Catalytic Mechanism. Protein Sci. 12, 532-537 (2003).
• Lloyd, J. A.*; Edmiston, P. L. Preferential Extraction of Hydrocarbons from Fire Debris Samples by Solid Phase Microextraction.  Journal of Forensic Sciences.  48, 130-134 (2003).
• Graham, A. L.*, Carlson, C. A.*, Edmiston. P. L. Development and Characterization of Molecularly Imprinted Sol-Gel Materials for the Selected Detection of DDT. Anal. Chem. 74, 458-467 (2002).
• Edmiston, P. L.. A New Start to Advanced Analytical Laboratory: Comparison of the Performance Characteristics of Various Instruments. J. Chem. Ed. 79(5), 616-618 (2002).
• Borders, C. L. Snider, M. J., Wolfenden, R., Edmiston, P. L. Determination of the Affinity of Each Component of a Composite Quaternary Transition-State Analogue Complex of Creatine Kinase. Biochemistry, 41, 6995-7000. (2002).
• Thompson, R. Q. and Edmiston, P. L. Ohio’s Crime Solvers: Analytical Chemistry Students Making the Case for Homicide.  Anal. Chem. 73, 678A-684A (2001).
• Edmiston, P. L., Schavolt, K. L.*, Kersteen, B. A.*, Moore, N. R.*,  Borders C. L. Kinetic Analysis of R95 Mutants of Rabbit Muscle Creatine Kinase, Biochem. Biophys. Acta, 1546, 291-298 (2001).
• Edmiston, P. L. and Williams, T. R.  An Analytical Experiment in Error Analysis: Repeated Determination of Glucose Using Commercial Glucometers. J. Chem. Educ.77, 377-379 (2000).
• Edmiston, P. L. and Saavedra, S. S.  Molecular Orientation Distributions in Protein Films III. Yeast Cytochrome c Films Immobilized on Pyridine Disulfide Capped Phospholipid Bilayers. Biophys. J. 74, 999-1006 (1998).
• Edmiston, P. L. and Saavedra, S. S. Molecular Orientation Distribution in Protein Films IV. A Multilayer Composed of Yeast Cytochrome c Bound through an Intermediate Streptavidin Layer to a Planar Supported Phospholipid Bilayer. J. Am. Chem. Soc. 120, 1665-1671 (1998).
• Wood, L. L.,  Cheng, S. S., Edmiston, P. L. and Saavedra, S. S.  Molecular Orientation Distributions in Protein Films II. Site Directed Immobilization of Yeast Cytochrome c on Thiol-Capped, Self-Assembled Monolayers.” J. Am. Chem. Soc. 119, 571-576 (1997).
• Edmiston, P. L., Lee, J. E., Cheng, S. S. and Saavedra, S. S.  Molecular Orientation Distributions in Protein Films. I. Cytochrome c Adsorbed to Substrates of Variable Surface Chemistry. J. Am. Chem. Soc. 119, 560-570 (1997).
• Edmiston, P. L. and Saavedra, S. S.  Fabrication and Characterization of Uranium Oxide Doped Sol-Gel Planar Waveguides for Attenuated Total Reflectance Spectrometry. Chem. Mater. 9, 2599-2603 (1997).
• Edmiston, P. L., Lee, J. E., Wood, L. L. and Saavedra, S. S.  Dipole Orientation Distributions in Langmuir-Blodgett Films by Planar Waveguide Linear Dichroism and Fluorescence Anisotropy.  J. Phys. Chem. 100, 775-784 (1997).
• Kölchens, S., Phiphivong, S., Edmiston, P. L. and Saavedra, S. S.  Time-Resolved Total Internal Reflection Fluorescence Microscopy of Cultured Cells using a Tb-Chelate Label.  Anal. Chim. Acta 307, 403-417 (1995).
• Edmiston, P. L., Wambolt, C., Smith, M. K. and Saavedra, S. S.  Spectroscopic Characterization of Albumin and Myoglobin Entrapped in Bulk Sol-Gel Glasses. J. Colloid  Interface Sci. 163, 395-406 (1994).
• Edmiston, P. L., Kolchens, S., Saavedra, S. S.  Temporally Gating a Slow-Scan CCD with a Liquid Crystal Shutter. Appl. Spectroscopy 47, 250 (1993).

(* denotes Wooster undergraduate)