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Tenative
Outline of how the Grant should progress
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| Week | What you should be doing | What's due when |
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Week 1 |
Introduction to the Grant writing project. Introduction to PP2B. You should ask me questions to make sure you know what PP2B is and what is expected for the grant | Assignment 1 - download and annotate full length Paramecium PP2B sequences from Genbank, Due on Friday |
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Week 2 |
This part of the lab will be part of your preliminary results. Make sure you understand what introns are, why it is important to verify their presence (and removal in the mRNA). |
Assignment 2 - align all paramecium PP2B sequences. Due on Friday Assignment 3 - identify introns in Paramecium PP2B sequences. Due on Friday. |
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Week 3 |
Look for what has been done in the classic model systems - mouse, zebrafish, drosophila, and C. elegans, and depth, meaning a number of papers have been published working on PP2B in that system. | Assignment 4 - Create table of similar PP2B sequences from other species. |
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Week 4 |
By this stage you should know what PP2B does biochemically and be able to provide some examples of the physiological functions for PP2B in other systems. |
Identify Assignment 6 partners (however, turn in separate assignment 4 and 5; be sure you have written them separately - do not write together!) |
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Week 5 |
You should use the informational literacy help session to round out and provide depth to your understanding as to what PP2B does in a variety of other systems. You should also have identified a review paper that provides a good summary of PP2B function. | Assignment 5. Your assignment is to provide a 2-page summary of what you have learned about the functions of the PP2B family in different species (yeast, mammals, other). Due on following Monday by 5:00 PM |
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Week 6 (schedule individual meetings) |
My comments should inform you as to the quality of yoru references, the quality of yoru writing and the depth of your analysis. If anything is unclear - arrange a meeting with me and take notes as to how to improve your summary. This summary will be the backbone of the introduction to your grant |
Return Assignment 5 on Friday |
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Week 7 |
A good peer review look at the total package and lets the authors know how we they have communicatedthe biochemical properties of PP2B and provided a comprehensive reveiw of PP2B function in a wide range of systems. |
Rough Draft of Backgorund section of the Grant due on Monday for Peer review. Schedule as working pairs. |
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Week 8
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Your background section should be taking shape and you should be beginning to make progress on your experimental design. You should have some ideas as to the types of experiments you will be proposing. | Peer evaluation returned.Meet to discuss grant Exp Design with Dr. Fraga. Come to the meeting with some examples of the types of experiments you might conduct. |
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Week 9 |
During this week you and your partner should be working together to finalize your background section and to get a good rough draft of your experimental design. Make sure you understand the various possibilities for thsi family (redundant, overlap, different functions) |
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Week 10 |
You should meet with Dr. Fraga to discuss his critique. Make sure you know what you are missing, what you are doing well and if you are headed in the right directions |
Faculty review of grant returned. M-F: Meet with Dr. Fraga to discuss grant between now and when next draft is due. |
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Week 11 |
Remember the goal of the experimental design is is to expand upon what we do in lab and to determine the functions of this gene family. |
Rough
Draft 2 for Peer review due on Monday. Return critique on Friday/discuss grant |
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Week 12 |
ReBegin to think about how you will present the results from lab in your grant and how your experimental design will build upon those results. |
Grant draft due on Friday for Faculty review. |
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Week 13 |
Arrange a meeting with Dr. Fraga so that you understand what you need to do to complet ethe assignment |
Grant returned. Meet with Dr. Fraga. |
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Week 14 |
Make sure you continue working on your grant with your partner. | Nothing due but arrange a meeting with Dr. Fraga |
| Week 15 | Finals week | Monday-Tuesday: meetings for grant. Final version of grant due on Thursday by 5:00 PM. |
Assignments 1-5 should be done individually. During week four we will identify who will be partners for the grant project. However, I want assignment 4 and 5 to be written individually so that I can assess the writing skills of each partner. The grant (assignment 6) can be done in pairs but throughout the assignment I will ask who wrote what and what each individual's contribution was. You will be required to evaluate your partner at the end of the assignment.
I will require that all drafts be collected in one notebook to be handed in at the end of the year. You should include all reviewer's comments and any responses you may have had to those comments. In addition, I request that you keep all of your collected materials in a separate notebook so that I can review it.
Copies of the previous year's grants are available for copying upon request.
Total points from the exercise - 200 points (Group project, Cumulative Grade)
This website was created by Dean Fraga (dfraga@acs.wooster.edu).