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Neurobiology Lecture & Lab Syllabus
Topic 1: Electrophysiology of the Neuron

Week 1 Introduction to Neurobiology (Chapters 1&2)

The neuron (Chapters 3&4)

Lab: Introduction to Lab and Journal club
Week 2 Electrical Signaling (Chapters 7&8) Lab: Discussion of Topics for journal club; assignment of dates and
topics
Week 3 Electrical Signaling within the Neuron (Chapters 8-10) Lab: AP Simulation Package - This will introduce you to some of the fundamental concepts of electrophysiology.
You will be introduced to the BioQuest CD-ROM interactive software concerning the Action Potential and the Nernst Equation. A brief lab notebook derived from the exercise will be completed.
Week 4 Electrophysiology Continued Lab: First journal club meeting
Lab: Golgi-Cox staining of rat brain (for 6 weeks later)
Topic 2: How neurons communicate and change their properties
Week 5 Introduction to Synaptic transmission (chapters 11&12) Lab: Second journal club meeting
Lab: Acetylcholine assay
Week 6 Synaptic integration & Modulation (chapters 13 & 14) Lab: Third journal club meeting
Lab: Earthworm electrophysiology
Week 7 Synaptic integration & Modulation (chapters 13 & 14)
Neurotransmitters and their release (chapters 15 & 16)
Lab: Fourth journal club meeting
Lab: Introduction to Paramecium electrophysiology

Week 8 Fall Break

Neurotransmitters and their release (chapters 15 & 16)

Lab: Fifth journal club meeting
Lab: Practice Paramecium behavioral tests
Topic 3: Neurophysiology and Cognition
Week 9 Introduction to the Nervous system and its development
(Chapters 5-6; parts of Ch. 25)
Lab: Practice Paramecium behavioral tests
Lab: Sixth journal club
Week 10 Cognitive Neural Science (Chapters 18&19)
Lab: Seventh journal club meeting
Lab: Sectioning the Golgi-Cox stained rat brain
Week 11 Sensory Systems (Chapter 20&21) Lab: Eigth journal club meeting
Lab: Paramecium Experiment 1
Week 12 Motor Systems (Chapter 26&27) Lab: Paramecium Experiment 2
Week 13 Learning and Memory (Chapter 35 &36 Lab: Paramecium Experiment 3
Week 14 Monday: Learning and memory: molecular aspects Lab: Thanksgiving

Week 15 Buffer
Lab: Poster of Paramecium experiments
Week 16 Finals Final is at