Independent Minds, Working Together
Julie Heck

Julie Heck

Visiting Assistant Professor

Department/Affiliation: Biology
Phone: 330-287-1958
Office Address: 304 Mateer
Email

Degrees

  • B.A., The College of Wooster 1997
  • Ph.D., Cornell University 2006

Courses Taught

  • IDPT 101: First Year Seminar
  • BIOL 200: Foundations of Biology
  • BIOL 201: Gateway to Molecular & Cellular Biology
  • BIOL 305: Cell Physiology

Interests

For the past several years, Julie's work has focused on understanding the mechanism of replication of a viral RNA genome, that of the hepatitis C virus (HCV). Working with purified proteins, she I studies interactions between host cell and viral proteins that promote HCV genome replication. Student projects have examined the mechanisms of HCV resistance to treatment. She has recently begun a new project studying genome stability in her favorite model organism, the budding yeast, Saccharomyces cerevisiae. Studies in yeast have yielded insight into the basic molecular mechanisms of a variety of pathways in eukaryotes. In this work, she is investigating mutations that alter the levels of nucleotides (DNA building blocks), and examining how they interact with other mutations to alter growth and genome stability. In mammals, altered nucleotide levels have been associated with cancer, and this basic research in yeast has the potential to inform our understanding of cancer prevention, formation and treatment.