Independent Minds, Working Together
Nicholas N. Shaw

Nicholas N. Shaw

Visiting Assistant Professor

Department/Affiliation: Chemistry
Phone: 330-287-1945
Office Address: 103 Severance
Email

Degrees

  • B.A., Chemistry, St. Olaf College, 2002
  • Ph.D., Organic Chemistry, Clemson University, 2010

Area of Research

  • Design and synthesis of therapeutic compounds
  • The form and function of nucleic acids
  • Targeting DNA:RNA hybrid structures
  • Teaching chemistry at the undergraduate level

Courses Taught

  • Chemistry 110: Introductory Chemistry
  • Chemistry 120: Principles of Chemistry
  • Chemistry 211: Organic Chemistry I
  • Chemistry 212: Organic Chemistry II

Awards & Professional Memberships

  • American Chemical Society

Publications

  • “Aminoglycoside Binding to A-form DNA.” Xi, Hongjuan; Shaw, Nicholas N.; Skriba, Michael; Arya, Dev P. Manuscript in preparation.
  • "Molecular Recognition of a DNA:RNA Hybrid: Sub-nanomolar Binding by a Neomycin-Methidium Conjugate." Shaw, Nicholas N.; Xi, Hongjuan.; Arya, Dev P. Bioorg. Med. Chem. Lett. 2008, 18(14), 4142-4145.
  • "Recognition of the Unique Structure of DNA:RNA Hybrids." Shaw, Nicholas N.; Arya, Dev P. Biochimie 2008, 90(7), 1026-1039.
  • “Novel Targets for Aminoglycosides.” In Aminoglycoside Antibiotics: From Chemical Biology to Drug Discovery. Ed. Arya, Dev P. New Jersey: John Wiley and Sons, 2007. 289-314.
  • “Neomycin improves cationic lipid-mediated transfection of DNA in human cells”. Napoli, S.; Carbone, G.M.; Catapano, C.; Shaw, N.; Arya, D.P.; Bioorg. Med.Chem.Lett. 2005, 15, 3467–3469.