Paul L. Edmiston

Paul L. Edmiston

Theron L. Peterson and Dorothy R. Peterson Professor of Chemistry, Analytical

Department/Affiliation: Chemistry, BCMB, Pre-Law Program
Phone: 330-263-2113
Office Address: 101 Severance
Curriculum Vitae (CV)


  • B.S., Pepperdine University 1993
  • Ph.D., University of Arizona 1997

Areas of Research

Advanced materials for water purification using mesoporous organosilica; development of chemical sensors based on molecularly imprinted materials. (There is an article in the Wooster Magazine Summer 2009 about Paul's research.)

Courses Taught

  • CHEM 101: Chemistry and the World in Which We Live (Forensic Science)
  • CHEM 111: General Chemistry I
  • CHEM 112: General Chemistry II
  • CHEM 215: Analytical Chemistry
  • CHEM 316: Instrumental Analysis
  • BCMB 303: Techniques
  • BCMB 401: Introduction to Independent Study
  • CHEM 401: Introduction to Independent Study
  • First Year Seminar

I.S. Projects

  • Rachel Bennett: Development of a Sensor for Gas-Phase Triacetone Triperoxide Using Waveguide Interferometry
  • Deanna Pickett: In Situ Remediation of Groundwater Contaminants Trichloroethylene and Perchloroethylene by Swellable Organo Silica-Nano Zero Valent Iron Composite Materials
  • Noél Mellor: Dosing on Demand: Enhanced Ibuprofen Release by an Organosilica Encapsulant
  • Rachel Molé: Investigation of Antidepressant Load Reduction Following Tertiary Wastewater Disinfection Treatment

Commercial Development Activities

ABSMaterials, Inc. Founded in 2008, ABSMaterials has applied Dr. Paul Edmiston's patented organosilica materials for water treatment, environmental remediation, and personal care.


Awards and Professional Memberships

  • Committee of Visitors, National Science Foundation, Division of Industrial Innovation and Partnership
  • 2011 Top 10 Breakthrough of the Year; Popular Mechanics Magazine (Osorb)
  • National Science Foundation (2010-11), "Produced Water Treatment Using Animated Organosilicas that Rapidly and Reversible Swell
  • Department of Energy, SBIR (2010-11), "Frac Fluid and Flow Back Water Treatment Using Animated Organosilicas that Rapidly and Reversible Swell
  • National Science Foundation RUI (2009-11), "Engineering Organosilica Materials that Rapidly and Reversible Swell for Water Remediation"
  • MIT Clean Energy Prize (2009), Finalist Team, Clean Hydrocarbons Category Winner
  • National Science Foundation EXP (2007-10)
  • National Science Foundation CAREER Award (2003-08)
  • American Chemical Society (ACS)


  • Sohn, H.; Celik, G., Gunduz, S; Dean, S. L.; Painting, E.*; Edmiston, P. L.; Ozkan, U. S. Hydrodechlorination of Trichloroethylene over Pd Supported on Swellable Organically-Modified Silica (SOMS). Appl. Catal. B. 203, 641-653 (2017).
  • Edmiston, P. L.; West, L. J.*, Chin, A.*; Mellor, N.*; Barth, D.*  Adsorption of Gas Phase Organic Compounds by Swellable Organically Modified Silica (SOMS). Ind. Eng. Chem. Res. 55, 12068-12079 (2016).
  • Edmiston, P. L.; Jolly, S. Nanoengineered Organosilica Materials for the Treatment of Produced Water.  In Aquananotechnology, Ed. David Reisner, CRC Press, Boca Raton, FL (2014).
  • Edmiston, P. L.; Swellable, Nanoporous Organosilica for Extended and Triggered Release, Cosmetics and Toiletries: Applied Science, 754-762 (2013).
  • Edmiston, P. L.; Osborne, C.; Reinbold, K. P.; Pickett, D. C.*; Underwood, L. A. Pilot Scale Testing Swellable Organosilica Nanoscale Zero-Valent Iron for In Sit Remediation of Trichloroethylene. Remediation, 22, 105-121 (2011).
  • Edmiston, P.L.; Keener, J.; Buckwald, S.; Sloan, B.; Terneus, J. Flow Back Water Treatment Using Swellable Organosilica Media. Proceedings of the Society of Petroleum Engineers, 2011, DOI. 10.2115/148973-MS.
  • Edmiston, P. L.; Campbell, D. P.; Gottfried, D. S.; Baughman, J.; Timmers, M. M.; Detection of Trinitrotoluene in the Parts-per-Trillion Range Using Waveguide Interferometry. Sensor & Actuators B, 143, 574-582 (2010).
  • Edmiston, P. L.; Underwood, L. A. Absorption of Dissolved Organic Species from Water Using Organically Modified Silica that Swells. Separation and Purification Technology, 66, 532-540 (2009).
  • Burkett, C. M.*; Underwood, L. A.*, Volzer, R. S.*; Baughman, J. A.*; Edmiston, P. L. Organic-Inorganic Hybrid Materials that Rapidly Swell in Non-Polar Liquids: Nanoscale Morphology and Swelling Mechanism. Chemistry of Materials 20, 1312-1321 (2008).
  • Jourden, M. J.*; Clarke, C. N.*; Palmer, A. K.*; Barth, E. J.*; Prada, R. C.*; Hale, R. N.*; Fraga, D. Snider, M. J.; Edmiston, P. L. Changing the Substrate Specificity of Creatine Kinase from Creatine to Glycocyamine: Evidence for a Highly Evolved Active Site”Biochim. Biophys. Acta, 1774, 1519-1527 (2007).
  • Walker, N. R.*; Linman M. J.*; Timmers, M. M.*; Dean S. L.*; Burkett, C. M.*; Lloyd, J. A.*; Keelor, J. D.*; Baughman, B. M.*; Edmiston, P. L.. Selective Detection of Gas-Phase TNT by Integrated Optical Waveguide Spectrometry Using Molecularly Imprinted Sol-Gel Sensing Films. Analytica Chimica Acta, 593, 82-91 (2007).
  • Ohren, J. F.; Kundracik, M. L.*; Borders, C. L.; Edmiston P. L.; and Viola R. E.  Structural Asymmetry and Intersubunit Communication in Muscle Creatine Kinase. Acta Cryst. D63, 381-389 (2007).
  • Carlson, C. A.*; Lloyd, J. A.*; Dean, S. L.*; Walker, N. R.*, Edmiston, P. L. Sensor for Fluorene Based on the Incorporation of an Environmentally Sensitive Fluorophore Proximal to a Molecularly Imprinted Binding Site, Anal. Chem., 78 (11), 3537 -3542 (2006).
  • Burkett, C. M.*; Edmiston P. L.; Highly Swellable Sol-Gels Prepared  by Chemical Modification of Silanol Groups Prior to Drying. J  Non-Crystalline Solids ,351 , 3174-3178 (2005).
  • Jourden, M. J.*; Geiss, P.*; Thomenius, M. J.*; Horst, L. A.*; Barty, M. M.*; Brym, M. J.*; Mulligan, G.B.*; Almeida, R.M.*; Kersteen, E.A.*; Myers, N.R.*; Snider, M. J.; Borders Jr., C. L.; Edmiston, P.L.; Transition State  Stabilization by Six Arginines Clustered in the Active Site of Creatine Kinase. Biochim. Biophys. Acta  ,1751 , 178-183 (2005).
  • Cox, J. M.*, Davis, C. A.*, Chan, C.*, Jourden, M. J.*, Jorjorian, A. D.*, Brym, M. J.*, Snider, M. J., Borders, Jr., C. L., Edmiston, P. L. Generation of an Active Monomer of Rabbit Muscle Creatine Kinase by Site-Directed Mutagenesis: The Effect of Quaternary Structure on Catalysis and Stability. Biochemistry 42, 1863-1871 (2003).
  • Borders, C. L.; MacGregor, K. M.*; Edmiston, P. L.; Gbeddy, E. R. K.*; Thomenius, M. J.*; Mulligan, G. B.*; Snider, M. J. Creatine Kinase: Asparagine 285 Plays a Key Role in Transition State Stabilization and Determination of the Catalytic Mechanism. Protein Sci. 12, 532-537 (2003).
  • Lloyd, J. A.*; Edmiston, P. L. Preferential Extraction of Hydrocarbons from Fire Debris Samples by Solid Phase Microextraction.  Journal of Forensic Sciences.  48, 130-134 (2003).
  • Graham, A. L.*, Carlson, C. A.*, Edmiston. P. L. Development and Characterization of Molecularly Imprinted Sol-Gel Materials for the Selected Detection of DDT. Anal. Chem. 74, 458-467 (2002).
  • Edmiston, P. L.. A New Start to Advanced Analytical Laboratory: Comparison of the Performance Characteristics of Various Instruments. J. Chem. Ed. 79(5), 616-618 (2002).
  • Borders, C. L. Snider, M. J., Wolfenden, R., Edmiston, P. L. Determination of the Affinity of Each Component of a Composite Quaternary Transition-State Analogue Complex of Creatine Kinase. Biochemistry, 41, 6995-7000. (2002).
  • Thompson, R. Q. and Edmiston, P. L. Ohio’s Crime Solvers: Analytical Chemistry Students Making the Case for Homicide.  Anal. Chem. 73, 678A-684A (2001).
  • Edmiston, P. L., Schavolt, K. L.*, Kersteen, B. A.*, Moore, N. R.*,  Borders C. L. Kinetic Analysis of R95 Mutants of Rabbit Muscle Creatine Kinase, Biochem. Biophys. Acta, 1546, 291-298 (2001).
  • Edmiston, P. L. and Williams, T. R.  An Analytical Experiment in Error Analysis: Repeated Determination of Glucose Using Commercial Glucometers. J. Chem. Educ.77, 377-379 (2000).
  • Edmiston, P. L. and Saavedra, S. S.  Molecular Orientation Distributions in Protein Films III. Yeast Cytochrome c Films Immobilized on Pyridine Disulfide Capped Phospholipid Bilayers. Biophys. J. 74, 999-1006 (1998).
  • Edmiston, P. L. and Saavedra, S. S. Molecular Orientation Distribution in Protein Films IV. A Multilayer Composed of Yeast Cytochrome c Bound through an Intermediate Streptavidin Layer to a Planar Supported Phospholipid Bilayer. J. Am. Chem. Soc. 120, 1665-1671 (1998).
  • Wood, L. L.,  Cheng, S. S., Edmiston, P. L. and Saavedra, S. S.  Molecular Orientation Distributions in Protein Films II. Site Directed Immobilization of Yeast Cytochrome c on Thiol-Capped, Self-Assembled Monolayers.” J. Am. Chem. Soc. 119, 571-576 (1997).
  • Edmiston, P. L., Lee, J. E., Cheng, S. S. and Saavedra, S. S.  Molecular Orientation Distributions in Protein Films. I. Cytochrome c Adsorbed to Substrates of Variable Surface Chemistry. J. Am. Chem. Soc. 119, 560-570 (1997).
  • Edmiston, P. L. and Saavedra, S. S.  Fabrication and Characterization of Uranium Oxide Doped Sol-Gel Planar Waveguides for Attenuated Total Reflectance Spectrometry. Chem. Mater. 9, 2599-2603 (1997).
  • Edmiston, P. L., Lee, J. E., Wood, L. L. and Saavedra, S. S.  Dipole Orientation Distributions in Langmuir-Blodgett Films by Planar Waveguide Linear Dichroism and Fluorescence Anisotropy.  J. Phys. Chem. 100, 775-784 (1997).
  • Kölchens, S., Phiphivong, S., Edmiston, P. L. and Saavedra, S. S.  Time-Resolved Total Internal Reflection Fluorescence Microscopy of Cultured Cells using a Tb-Chelate Label.  Anal. Chim. Acta 307, 403-417 (1995).
  • Edmiston, P. L., Wambolt, C., Smith, M. K. and Saavedra, S. S.  Spectroscopic Characterization of Albumin and Myoglobin Entrapped in Bulk Sol-Gel Glasses. J. Colloid  Interface Sci. 163, 395-406 (1994).
  • Edmiston, P. L., Kolchens, S., Saavedra, S. S.  Temporally Gating a Slow-Scan CCD with a Liquid Crystal Shutter. Appl. Spectroscopy 47, 250 (1993).

(* denotes Wooster undergraduate)